Eisenhower was concerned about Big Science, driven by massive government funding. His concern in the 1950s was the military-industrial complex, although he appreciated the need to keep ahead of the Evil Empire he could see what was happening to the incentives for scientists. A government grant could substitute for curiosity.
I went after this for the warning about government funded science but there is other good stuff as well. Interesting comparison with the current incumbent.
Speech notes for his 1961 farewell address.